Ultrasound Guided Thoracic Paravertebral Block for Hepatic Tumors Ablation

Mahidol University35 enrolled

Overview

Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control. TPVB is suitable for unilateral operations. And it is increasing popular nowadays because of using ultrasound guided which make it is more reliable and has less side effects especially the severe one such as pneumothorax. To cover all nerve supply liver, we decided to use right TPVB at T5-6, T7-8, and T9-10. The aim of this study is to prove that TPVB can provide an effective pain control for patients undergo liver RFA both at rest and movement (cough). We are going to measure the pain score at recovery room and the effective pain control means patients has mild pain (pain score less \</= 3 and do not ask for analgesic drugs).

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Liver Cancer

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years * Patients undergo percutaneous radiofrequency ablation for liver tumors * ASA classification 1-3 Exclusion Criteria: * Psychiatric illness * Chronic abdominal pain \> 1 week * Regular analgesic drugs use * Infection at back (Block area) * Severe spinal deformity * PT \> 16 sec, aPTT \> 32, platelet \< 50,000/cumm

Outcomes

Primary Outcomes

pain score at recovery room both at rest and movement (cough)

All patients at recovery room has mild pain (pain score \</= 3) and do not need any rescue analgesic drugs.

Time frame: Up to 24 hours

Secondary Outcomes

Distribution of local anesthetic drugs after performing ultrasound guided TPVB at T5-6, T7-8 and T9-10.

Test with cold sensation.

Time frame: After performing TPVB at 5, 10, 20 and 30 minutes.