The purpose of the study is to evaluate the clinical outcomes and cost-effectiveness of different vascular access(arteriovenous fistula, tunneled cuffed catheter and arteriovenous graft) in the elderly and very elderly with end-stage renal disease in China.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
500
Shanghai Changzheng Hospital
Shanghai, China
The patency rate of vascular access
Including primary and secondary patency rate.Blood flow can be above 500 mL/min in a mature arteriovenous fistula by ultrasound scan and 4 times of body weight (Kg\*4 mL/min) in a arteriovenous graft or tunneled cuffed catheter in dialysis practice.
Time frame: 2 years
Effect of vascular access construction on ventricular volumes and left ventricular remodeling
Assessed by doppler echocardiography
Time frame: 2 years
Effect of vascular access construction on brain MRI and cognitive functionslesions and cognitive function
Cognitive functions are assessed by psychic and autonomy scores
Time frame: 2 years
Complications of vascular access
Described as %.Complications including bleeding, infection, thrombosis, artery steal syndrome, heart failure, inadequate dialysis, etc.
Time frame: 2 years
Cost-effectiveness of different vascular access
Described as $.The cost including medical expenses and non-medical expenses.
Time frame: 2 years
Hospitalization rate due to vascular access.
Time frame: 2 years
Mortality due to vascular access
Time frame: 2 years
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