Comparative Study of Specular Microscopes for Measurements of Cell Density, Coefficient of Variation and Hexagonality

Inclusion Criteria: * Non-Pathologic: Male or female subjects from 18 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site,and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study. * Pathologic: Male and female subjects from 29 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site, and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study. At least one eye with any of the following conditions: * History of post-op surgical trauma including bullous keratopathy * History of corneal transplant * Physical injury or trauma to the cornea * Long term Fuch's dystrophy, Guttata or other corneal endothelial dystrophies * Keratoconus * Long term PMMA contact lens use (greater than 3 years) Exclusion Criteria: * Non-Pathologic: Male and female subjects from 29 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site, and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study. At least one eye with any of the following conditions: * History of post-op surgical trauma including bullous keratopathy * History of corneal transplant * Physical injury or trauma to the cornea * Long term Fuch's dystrophy, Guttata or other corneal endothelial dystrophies * Keratoconus * Long term PMMA contact lens use (greater than 3 years) * Pathologic: History of cataract, refractive or ocular surgical procedures that render the cornea opaque or otherwise impact its ability to be imaged using the investigational device. Fixation problems which may prevent obtaining at least poor quality (refer to Figure 1) CEM-530 and KONAN CELLCHEK PLUS images in either eye.