Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy

Second Xiangya Hospital of Central South University40 enrolled

Overview

The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness

In the study ,primary angle closure(PAC) and primary angle closure glaucoma (PACG) will be recruited. Anterior segment optical coherence tomography images captured before and after laser peripheral iridotomy will be analysed to provide objective and reproducible quantification of anterior segment biometric parameters.The outcomes can provide useful information for clinical strategies in the treatment and management of pathology related to angle closure.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Primary Angle Closure Glaucoma

Interventions

Laserex Tango Nd:YAG, Ellex-SuperQ Medical, AustraliaPROCEDURE

All the patients will be achieved with pilocarpine 1% for pupil constriction, laser peripheral iridotomy(LPI) is performed using the ophthalmic neodymium: yttrium aluminium garnet laser (Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia) and an VOLK iridotomy contact lens. After LPI, patients will be given topical prednisolone acetate 0.1% for 7 days.

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1 .The gonioscopy or UBM examination has confirmed the diagnosis of PACS or PAC 2. Intraocular pressure within 10 to 21 mmHg ，C/D≤0.6 3. Visual field is normal or only show paracentral scotoma 4. Vision or corrected visual acuity ≥0.8 5. Refractive degree no more than 200D 6. Exclude other ocular and systemic diseases \- Exclusion Criteria: 1. Corneal macula and other corneal diseases, ocular surface disease or corneal edema 2. Iridocyclitis 3. Ocular trauma and intraocular operation history 4. No fixationFundus lesions such as diabetic retinopathy or retinal detachment 5. No fixation 6. Ocular or systemic application of cortical steroids -

Locations (1)

The Second Xiangya Hospital of Central South University,

Changsha, Hunan, China

RECRUITING

Outcomes

Primary Outcomes

Changes in anterior chamber after LPI at 1 month

Time frame: 1month

Central Contacts

Haomin Luo, Ph.D student

CONTACT

+86 13875830738 lhmqqpp@163.com

Data from ClinicalTrials.gov

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