PINS Stimulator System for Deep Brain Stimulation of the Nucleus Accumbens to Treat Severe Opioid Addiction

Inclusion Criteria: 1. Age \> 18 years old. 2. In accordance with the diagnostic standards of DSM-IV \& ICD-10 for addicted and DSM-IV for abstinence. 3. Qualitative urine detection for opioids showing positive result. 4. Cleared for 8 to 36 hours after their last drug taking. 5. Fully understood and signed on informed consent. Exclusion Criteria: 1. Person with consciousness disorder on opioid abstinence, seriously aggressive, heavily dehydrated and intending to commit suicide. 2. Patients with serious liver and kidney dysfunction, pulmonary decompensation, or complicated with serious damage in other systems. 3. Patients with serious infectious disease. 4. Patients with history of serious neurological or psychiatrical diseases. 5. Person with history of HIV infection or serious malnutrition. 6. Dependent upon and addicted to multiple drugs. 7. Attended some other drug trials within one month.