Dexmedetomidine Adjuvant in Retinal Surgery

King Saud University90 enrolled

Overview

During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl . The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Peribulbar Anesthesia

Interventions

DEXMEDETOMIDINEDRUG

Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?

Eligibility

Sex: ALLMin age: 40 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients * Going for elective vitreoretinal surgery. Exclusion Criteria: * History of coagulation abnormalities. * Allergy to local anesthetics. * Cardiac, hepatic or renal failure, * Chronic clonidine or analgesic therapy. * One-eyed patients

Locations (1)

King Abdulaziz University Hospital at King Saud University

Riyadh, Riyadh Region, Saudi Arabia

Outcomes

Primary Outcomes

onset, duration of the motor and sensory block

A block was considered satisfactory when complete akinesia occurred. In the absence of complete akinesia in any direction after 10 min, supplementary anesthesia given by a further injection of 2-4 ml of the test solution in the same manner as given before. Calculate the number of patients needed supplemental block were. The surgeon assessed the duration of surgery anesthesia and akinesia. Intraocular pressure measured before block, immediately after block and before surgical procedures

Time frame: 10 minutes from injection

Secondary Outcomes

observe the adverse effects of Dexmedetomidine

ECG, invasive BP and pulse oximetry will apply to all patients. • The haemodynamic parameters (MAP and HR) will be continuously measured, and will be recorded at before induction (baseline), one minute after block . after 5 minutes then at the surgical incision, 15-min intervals intraoperatively, the end of surgery and10 and 20 minutes postoperatively. Incidence of Oculocardiac reflex (OCR) or any arrhythmia during surgery.

Time frame: during and after surgery

Data from ClinicalTrials.gov

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