Exploring Efficacy of Intensive Rosuvastatin Treatment Peri-PCI in Chinese Patients With Non ST-segment Elevated Acute Coronary Syndrome(NSTE-ACS)

Inclusion Criteria: 1. 18-80 year old males and non-child-bearing period females. 2. Clinical diagnosed with NSTE-ACS, including unstable angina or non-ST-segment elevation myocardial infarction(NSTEMI). * For unstable angina, the diagnose should meet all below: Clinical onset features: angina for at least 20 min when resting; initial onset angina pectoris(new onset within one month) manifests spontaneous angina or labor angina (CCS grade II or III); Symptoms of original stable angina pectoris aggravate in one month and at least achieve CCS grade III (accelerated angina pectoris); angina onset within one month after MI. ECG: At least twice in one month: ST depression or elevation \>0.1millivolt (mv) or T-wave inversion ≥0.2 mv in 2 or more contiguous electrocardiographic leads when onset and the ST-T changes recovered after remission of chest pain. Myocardial damage marker do not elevate or reach the MI diagnostic level. * For NSTEMI, the diagnose should meet all below ischemia symptoms(ischemic chest pain lasting more than 30 min and cannot relief significantly by sub-lingual NTG) ECG change: new ST-T dynamic development (new or transient ST depression ≥0.1mv or T-wave inversion≥0.2mv). Myocardial damage marker level is normal or elevated to the MI diagnostic level. 3. Received early (within 48 h) Percutaneous Coronary Intervention(PCI). 4. Should be statin- naïve(last 3 months). 5. Only receive drug-eluting stents. 6. Sign the Informed Consent Form(ICF) Exclusion Criteria: Any of the following is regarded as a criterion for exclusion from the study: 1. Diagnosis as STEMI; 2. NSTE-ACS with high-risk features warranting emergency coronary angiography; 3. Receive only medical therapy or Coronary Artery Bypass Graft(CABG) 4. Active liver disease or dysfunction including agnogenic serum transaminase sustained elevation or higher than 3 times upper limit of normal(ULN); 5. Left ventricular ejection fraction\<30%; 6. Previous or current treatment with statins; 7. Patients with myopathy or serum creatine kinase \> 5 times the upper limit of normal not caused by myocardial injury; 8. Severe renal function damage (creatinine clearance rate\<30 ml/min); 9. Severe anemia (haemoglobin\< 6g/L); 10. Diagnosed with malignancy within 5 years; 11. Concurrent use ciclosporin； 12. Investigator evaluated as not appropriate for statins.