Epithelial cancer of the ovaries is the most severe form of gynecologic cancer; a significant proportion of ovarian cancers originate from the Fallopian tube. Guidelines therefore now recommend systematically associating prophylactic salpingectomy to benign hysterectomy. The principal objective of the present study is to assess the impact of salpingectomy on ovarian reserve by anti-Müllerian hormone (AMH) assay and calculating the Doppler index of vascular resistance in the ovarian vessels. The secondary objective is to compare ovarian reserve results between two coagulation techniques used in salpingectomy: bipolar electric energy versus ultrasound. The study design is single-center, prospective, before-and-after, with open randomization between two groups defined by coagulation technique.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
96
Coagulation during salpingectomy using conventional bipolar electric energy
Coagulation during salpingectomy using UltraCision HARMONIC ACE® ultrasound energy
Hospices Civils de Lyon - HFME
Lyon, France
AMH level
Time frame: 3 months post-surgery
AMH level
Time frame: 1 month post-surgery
index of vascular resistance in the ovarian vessels
Time frame: 1 and 3 months post-surgery
menopausal quality of life score
Time frame: 1 and 3 months post-surgery
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