A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLD

Inclusion Criteria: 1. Type Ⅱ diabetes mellitus 2. Non-alcoholic fatty liver disease: subjects who have CAP(Controlled Attenuation Parameter) ≥ 250dB/m measured by transient elastography (fibroscan) at screening test 3. Age ≥ 20 years 4. Patients who have not been taking any oral hypoglycemic agent for more than 12 weeks with HbA1c 7.0 to 8.5% at screening test or who have been taking metformin monotherapy for at least 8 weeks with HbA1c 7 to 9% at screening test 5. Agreement with written informed consent Exclusion Criteria: 1. Patients whose alcohol consumption \>210g/week for males and 140g/week for females 2. chronic B viral hepatitis, chronic C viral hepatitis, Type I diabetes, or secondary diabetes 3. having a history of acute or chronic metabolic acidosis including diabetic ketoacidosis 4. patients who have been taking other oral hypoglycemic agents except metformin or insulin within recent 8 weeks 5. who experienced hypersensitivity reaction against metformin or glitazone drugs 6. who has been treated with corticosteroids for at least 14 days within 2 month prior to Screening 7. having a history of lactic acidosis 8. having genetic predispositions such as galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption 9. who are in condition of malnutrition, starvation, cachexia, severe infection, major trauma, hypopituitarism, or adrenal insufficiency 10. diagnosed with cancer within 2 years or having chemo or radiotherapy for cancer treatment 11. a history of drug abuse or chronic alcoholism 12. a history of heart failure (NYHA class III and IV) or uncontrolled arrhythmia 13. a history of acute cardiovascular or cerebrovascular disease within 12 weeks prior to Screening (unstable angina, myocardial infarction, transient ischemic attack, cerebral infarct, cerebral hemorrhage, coronary bypass, percutaneous coronary intervention) 14. Renal dysfunction: Serum creatinine greater than 1.5mg/dl for males and 1.4mg/dl for females. 15. Anemia less than 10.5g/dl for any reason 16. Pregnant women or nursing mothers 17. Fertile women who not practice contraception with appropriate methods 18. in treatment concomitant drug from other clinical trials within 4 weeks from enrollment 19. who did not agree with written informed consent