A Comparative Study of the Healing of Chronic Ulcers of Recessive Epidermolysis Bullosa : Dressing vs Amniotic Membrane

Inclusion Criteria: * Age between 2 years and 60 * REBD clinically evident with immunohistological confirmation and / or genetic * REBD with at least two chronic ulcers (\> 3 months) comparable * Signing the informed consent of the patient and / or (children) of parents holding parental authority * Affiliation to a social security scheme (beneficiary or legal) Exclusion Criteria: * Epidermoid carcinoma on the target or chronic ulcers * Budding excessive requiring the application of a topical corticosteroid on the target or chronic ulcers * Skin bacterial superinfection clinically overt requiring oral antibiotics * Herpes simplex virus superinfection * major evolutionary and malnutrition defined as a BMI \<12 or more than 2 variant between screening and randomization OR a serum albumin \<20 g / l or more ranging from 5 g / l between screening and randomization * major and progressive anemia defined by a Hb \<6 g / liter or variant more than 4 g / l between screening and randomization * Life expectancy estimated at less than 3 months * Pregnancy * Inability to understand or observance of the rules of protocol * Participation in another interventional therapeutic biomedical research whose treatment is not yet completed or the primary endpoint is not yet measured at the time of inclusion in Mabul