The primary purpose was to describe the acid base balance of ICU patients with severe hypoalbuminemia using Stewart's approach for acid base disorders, before and after an human albumin perfusion.
Prospective study, for ICU patient with severe hypoalbuminemia \< 20g/L, determining biological parameters from Stewart approach for acid base disorders (pH, SIDe, SIDa, SIG, Atot, PaCO2) before, and at 1hour, 2hours and 24 hours after a 200mL 20% human albumin perfusion (the consensus conference ANAES of 1995 recommands to correct hypoalbuminemia below 20g/L). Clinical parameters (respiratory, haemodynamic, neurologic) were also collected at the same times.
Study Type
OBSERVATIONAL
Enrollment
100
Prospective study, for ICU patient with severe hypoalbuminemia \< 20g/L, determining biological parameters from Stewart approach for acid base disorders (pH, SIDe, SIDa, SIG, Atot, PaCO2) before, and at 1hour, 2hours and 24 hours after a 200mL 20% human al Clinical parameters (respiratory, haemodynamic, neurologic) were also collected at the same times.
CHU de Clermont-Ferrand
Clermont-Ferrand, France
changes in pH and independent pH determinants using Stewart approach
Time frame: at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion.
changes in neurologic parameters
Time frame: at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion.
changes in hemodynamic parameters
Time frame: at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion.
changes in respiratory parameters
Time frame: at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion.
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