Interventional Bronchoscopy Under Noninvasive Ventilation

Futian People's Hospital40 enrolled

Overview

To evaluate the effect and safety of noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis. With the sedation and analgesia, noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis is safe and effective, carries high satisfaction rate.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Noninvasive Positive Pressure Ventilation;Sedation;Bronchoscopy；Interventional；Central Airway Stenosis

Interventions

invasive ventilationPROCEDURE

interventional bronchoscopyPROCEDURE

noninvasive ventilationDEVICE

sedation(dezocine and midazolam)DRUG

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * (a)patients with central airway stenosis need interventional bronchoscopy. (b) partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio less than 300; Exclusion Criteria: * (a) facial deformity sufficient to preclude mask fitting; (b) upper gastrointestinal bleeding; (c) upper airway obstruction; (d) acute coronary syndromes; (e) tracheostomy or endotracheal intubation(ETI) before admission; (f) need for urgent ETI due to cardiac or respiratory arrest.

Locations (1)

Futian People's Hospital

Shenzhen, Guangdong, China

RECRUITING

Outcomes

Primary Outcomes

The improvement of airway stenosis after the operation

Time frame: 1 day

The improvement of partial pressure of arterial oxygen (PaO2) after the operation

Time frame: 1 day

Secondary Outcomes

hospitalization expenses

Time frame: During the period of hospitalization，an expected average of 4 weeks

hypoxemia during the operation

Time frame: 1 day

Central Contacts

Xiao-ke Chen, Master

CONTACT

+86-755-83982222 007cxk@163.com

Data from ClinicalTrials.gov

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