Tolerance and Pharmacokinetics of T0001 in Healthy Adult Chinese Volunteers

Inclusion Criteria: * Healthy adult volunteers, able to give written informed consent for participation in the trial; * Men or women 50% each , aged 18-45 years old; * Subjects must have physical examination required and prove medical fitness in 7 days before the clinical starts. BMI should be between 19-24, similar BMI among subjects enrolled at the same time; Exclusion Criteria: * Acute or chronic infection, or history of active tuberculosis; * History of diseases of central nervous system, cardiovascular system, kidney, liver ( specified liver function index), digestive system, respiratory system , metabolism system; * Subjects who use 5 Unit doses tuberculin skin test are positive( 48-72 hour scleroma reading≥5mm); * Subjects with a history of mental problems; * Pregnant and lactating women or women who plan to be pregnant in 3 months; * Occurence of clinical significant abnormal laboratory examination value during the screening; * Subjects that lack of understanding ,communication or collaboration, and can't comply with the protocols; * Subjects that the researchers considered to be not appropriate to participate the trial due to other reasons;