The purpose of this study is to compare the contrast agents and imaging techniques used for thoracoabdominal aortic imaging in CT. Imaging parameters and contrast volume are changed and adjusted based on the contrast agent, since contrast agents have varying iodine concentrations. If the contrast iodine concentration is higher, it may be possible to adjust the imaging parameters and lower the overall radiation dose to the patient.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
150
iodine contrast
Duke University Medical Center
Durham, North Carolina, United States
Radiation Dose
Time frame: 30 minutes
Signal to Noise Ratio
Calculated as the ratio of mean attenuation values divided by the standard deviation of attenuation values gathered using a circular region of interest in the thoracic aorta.
Time frame: 30 minutes
Hounsfield Unit Attenuation Values
Grayscale values on CT scans are given as Hounsfield units. These Hounsfield units reflect the attenuation of x-ray beams traversing the aortic lumen. We will use Hounsfield units to assess whether the tool contrast agents achieve similar attenuation characteristics essential for diagnosing aortic abnormalities. We will use circular regions of interest in the thoracic aorta to extract the Hounsfield unit measurements.
Time frame: 30 minutes
Variation in Contrast for the Entire Vascular System (coV)
The change in contrast was measured at the proximal segment of the aorta and at the Iliac arteries for each subject.
Time frame: 30 minutes
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