Study, Double Blind, Randomized, Comparing Two Groups to Evaluate the Safety and Efficacy of Autologous Mesenchymal Stem Cells From Adipose Tissue (CMMAd) in the Treatment of the Faecal Incontinence

Inclusion Criteria: 1. Males or females in the age group of 18-80 yrs. 2. A unique internal sphincter defect and / or external (no more than 100 º), at any level of the anal canal, of any cause (except those described in the exclusion criteria). 3. Severity of faecal incontinence of 12 or more in the Wexner Score and / or at least six episodes of faecal incontinence for a period of 28 days. 4. Duration of faecal incontinence of at least two years prior to inclusion. 5. Patients who are able to understand the requirements of the study, and willing to provide voluntary written informed consent. Exclusion Criteria: 1. More of an external sphincter defect and / or at any level of internal anal canal. 2. Have received treatment to faecal failure with bulking agents, neuromodulation or surgery. 3. Current anorectal tumors. 4. Current anal fissures. 5. Anorectal stenosis 6. Chronic pelvic or anorectal pain. 7. Pregnant or 6 months postpartum. 8. Medical history of infection with Human Immunodeficiency Virus (HIV) or any severe immunocompromised state or therapy immunosuppressive. 9. Malignancies in remission for less than a year before the study. An exception to the basocellular carcinoma (BCC) in "remission" for less than a year. 10. Bleeding diathesis or current anticoagulant therapy. 11. Chemotherapy during the 6 months preceding the study. 12. Previous radiation with evidence of radiation injury in the treated area. 13. Participation in any other clinical study during the 3 months preceding the pre-study visit. 14. Patients with other serious disorders. 15. Patients with uncontrolled inflammatory disease or taking drugs prohibited in the protocol or active perianal disease.