The risk-benefit of surveillance-protocol biopsy (SPBx) in kidney transplantation remains unclear. The study aims to compare outcomes of recipients with SPBx approach to recipients with standard approach which allograft biopsy was performed only when indicated.
The present randomized-controlled trial in kidney transplant patients aims to compare the outcomes and complications between who underwent immunosuppessive drug modification under surveillance-protocol biopsy and who underwent immunosuppressive drug modification following tough level only.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
100
Surveillance protocol biopsy under ultrasound-guided will perform at post-operative day 7, month 3, month 6, month 12, and month 24
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University
Bangkok, Bangkok, Thailand
RECRUITINGRenal function
24 h-CrCl
Time frame: 24 months
Renal pathology
interstitial fibrosis, rejection, calcineurin inhibitor toxicity
Time frame: 24 months
Complications
hematoma, arteriovenous fistula
Time frame: immediate, 1 month
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