Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity and Mortality

Inclusion Criteria: Patients with cirrhosis who have been diagnosed by clinical, biochemical,or histological (when available) criteria plus ultrasound imaging. * Age range of 18-60 years * Cirrhosis as diagnosed by histology or clinical, laboratory and USG (UltraSonography) findings, * Upper GI bleed who are undergoing secondary endoscopic variceal ligation for eradication of varices Exclusion Criteria: * Age \>60 years * Chronic renal disease * Pregnancy and peripartum cardiomyopathy * Hypertension * Coronary artery disease * Valvular heart disease * Sick sinus syndrome/ Pacemaker * Cardiac rhythm disorder * Hypothyroidism * Hyperthyroidism * Portal vein thrombosis * Transjugular intrahepatic porto systemic shunt (TIPS) insertion * Hepatocellular carcinoma * Anemia Hb \< 8gm/dl in females, and \< 9 gm/dl in males