Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach

Lionel Bouvet28 enrolled

Overview

The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency trauma surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Emergency Surgery Full Stomach

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Emergency surgery for trauma * ASA 1 and 2 patients * Full stomach (antral area \> 550 mm²) * Adult patients Exclusion Criteria: * No contraindication to erythromycin * Extreme emergency surgery (time frame \< 90 min between arrival in the service and the start of the surgery) * gastroparesis or pathology associated with gastroparesis

Locations (1)

Hopital Edouard Herriot

Lyon, France

Outcomes

Primary Outcomes

ultrasonographic measurement of antral area

Time frame: 30 minutes and immediately before erythromycin infusion, and 30, 60 and 90 min after the start of erythromycin infusion

Data from ClinicalTrials.gov

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