Rapid Sequence Intubation at the Emergency Department

University of Zurich150 enrolled

Overview

All patients undergoing emergent endotracheal intubation (RSI) at the Emergency Department will be screened for inclusion in this clinical study. The indication of endotracheal intubation is an exclusively clinical decision and is not affected by this study protocol in any aspect. If fulfilling the In- and exclusion criteria's, patient will be randomly assigned to one of two groups 1. C-MAC Videolaryngoscope in appropriate size 2. conventional endotracheal intubation using Macintosh Blade in appropriate size Randomization (1:1) will be based on computer-generated codes maintained in sequentially numbered opaque envelopes that will be opened immediately before randomization.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

150

Conditions

Emergency

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients requiring emergency Rapid Sequence Intubation at the emergency department * Male and Female subjects 18 years to 99 years of age * Written confirmation by a physician not involved in this study * Written informed consent by the participant (obtained afterwards) * Patient not showing remarkable rejection in participation in this study Exclusion Criteria: * Maxilla-Facial trauma * Immobilized cervical spine * Indication for fiberoptic guided intubation (known difficult airway) * Ongoing Cardio-Pulmonary-Resuscitation (CPR) * Involvement in any other clinical trial during the course of this trial, within a period of 30 days prior to its beginning or 30 days after its completion * Severe or immediately life-treating injury requiring immediate medical treatment

Outcomes

Primary Outcomes

Success Rate

defined as successful placement of endotracheal tube within the trachea and

Time frame: 10 minutes

Secondary Outcomes

time to intubation

defined as time between insertion of the videolaryngoscope/ Macintosh blade into the mouth until detection of end-tidal CO2

Time frame: 10 minutes

Laryngoscopic view

Cormack and Lehane Score

Time frame: 10 minutes

Number of intubation attempts

Time frame: 10 minutes

Unrecognized esophageal intubation

Time frame: 10 minutes

Ease of intubation (1-5)

o (1) very easy, (2) easy, (3) somewhat difficult, (4) difficult, (5) impossible

Time frame: 10 minutes

Violations of the teeth

number of patients; teeth will be inspected for potential damage and documented accordingly

Time frame: 10 minutes

Necessity of using further, alternative airway devices for successful intubation (if randomized airway device failed)

number of patients, requiring alternate device

Time frame: 10 minutes

Maximum drop of saturation

Spo2 will be measured continuously and documented accordingly

Time frame: 10 minutes

Rapid Sequence Intubation at the Emergency Department

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes