Aeroneb Solo Adapter is a vibrating-mesh nebulizer Aeroneb Solo combined to a spacer specifically designed for spontaneously breathing patients. This device has not been investigated in vivo yet. It's known that using a spacer during nebulization improves aerosol delivery. We hypothetized that lung deposition could be highly increased with the Aeroneb Solo Adapter in comparison to a standard jet nebulizer.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
6
Solution placed on the nebulizer reservoir
Nebulizer
Standard jet nebulizer
Cliniques Universitaires Saint-Luc
Brussels, Belgium
Pulmonary deposition
Planar scintigraphy and single photon emission computed tomography as imaging techiques
Time frame: immediately after nebulization by imaging assessment, an expected average of 15 minutes
Three-dimensional penetration index
Single photon emission computed tomography as imaging technique
Time frame: immediately after the nebulization by imaging assessment, expected average of 30 minutes
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Imaging technique to investigate whole lung deposition
Imaging technique to investigate regional pulmonary deposition
FEV1, FVC assessment