Surgical Infection Rates With Adjunct Vancomycin Compared to Standard Peri-Operative IV Antibiotics

N/AUnknownNCT02299882

Corewell Health West700 enrolled

Overview

Determine the effect of Vancomycin Powder added to the surgical wound at closure on surgical infection rates.

Study will be blinded and randomized 1:1 to either Vancomycin Powder at closure or no vancomycin powder at closure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

700

Conditions

Lumbar Pain

Interventions

VancomycinDRUG

Patient will be randomized to either vancomycin or no vancomycin. This treatment will take place prior to the closure of the incision from back surgery.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All adult, 18 years or greater undergoing posterior approach spinal surgery Exclusion Criteria: * Prisoner, pregnant women, patient under the age of 18, those of diminished decision making capacity. * patients with known reaction to Vancomycin. * patients having surgery specifically for spine infection * patients having ADCF or ALIF

Locations (1)

Spectrum Health Hospitals

Grand Rapids, Michigan, United States

RECRUITING

Outcomes

Primary Outcomes

Surgical wound infection rate, both deep and superficial infections

Time frame: 12 weeks post surgery

Secondary Outcomes

Post-operative rate of MRSA infections.

Time frame: 12 weeks post surgery

Data from ClinicalTrials.gov

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