The purpose of the study is evaluating safety and clinical efficiency of full femtosecond laser-assisted anterior lamellar keratoplasty (FS-ALK) for curing patients with keratoconus and corneal opacities
Keratoplasty is the most widely spread tissue transplantation procedure. Although penetrating keratoplasty (PKP) is still commonly used for curing corneal dystrophy and opacities of different genesis, lamellar techniques provide significant advantages in terms of safety and predictability. Al in all 13 FS-ALK procedures were performed for 11 eyes with advanced keratoconus and 2 eyes with superficial corneal scattering Before and after surgery uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), postoperative astigmatism, endothelial cell loss, central cornea thickness, residual recipient's tissue thickness, corneal hysteresis (CH) and corneal resistance factor (CFR) were evaluated . At 1-year follow-up Confoscan investigation of donor-recipient interface was performed. All FS-ALK procedures were performed with Intralase FS 60kHz femtosecond laser in a following way. At first a 80% thickness corneal graft was prepared. Then maximum thickness recipients corneal dissection was performed according to OCT (optical coherence tomography) data and superficial tissue was removed. Transplant was fixed in a resulted bed by continuous suture.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
13
The procedure was a non-penetrating transplantation of 80% thickness corneal graft
Mean endothelial cell loss
Time frame: 12 months after surgery
Mean postoperative astigmatism
Time frame: 12 months after surgery
UCVA (uncorrected visual acuity)
Time frame: 12 months after surgery
BSCVA (best spectacle-corrected visual acuity)
Time frame: 12 months after surgery
Corneal hysteresis
Evaluation of biomechanical qualities of the cornea
Time frame: 12 months after surgery
Corneal resistance factor
Evaluation of biomechanical qualities of the cornea
Time frame: 12 months after surgery
Central corneal thickness
measured by OCT (optical coherence tomography - Optovue)
Time frame: 12 months after surgery
Residual recipient's tissue thickness
measured by OCT (optical coherence tomography - Optovue)
Time frame: 12 months after surgery
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