Biological Markers Predicting Exercise Capacity in CF-LVAD Patients.

Rigshospitalet, Denmark25 enrolled

Overview

Establishing the association between biological markers and exercise capacity in continuous-flow left ventricular assist device patients.

The aim of this study is to investigate if specific biological markers can predict exercise capacity in advanced heart failure patients supported with continuous-flow left ventricular assist device patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Heart Failure

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stable CF-LVAD patients. Exclusion Criteria: * Unstable CF-LVAD patients.

Locations (1)

University Hospital Rigshospitalet.

Copenhagen, Kbh Oe, Denmark

Outcomes

Primary Outcomes

Biological markers

Analysis of blood will be carried out on all samples simultaneously, expected markers are pro-BNP, MRproANP, copeptin, Gal-3 and proADM.

Time frame: Blood sampling on study day and samples are subsequently stored frozen.

Secondary Outcomes

Exercise capacity

Exercise capacity will be estimated by peak VO2 measurements on a upright ergometer bike with breath-by-breath gas analysis.

Time frame: Examination on study day. Patients will only be followed on the day of the study. Exercise testing is performed as the last intervention on the study day.

Data from ClinicalTrials.gov

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