CO2 Laser and Open Surgery for T1N0 Glottic SCC With Anterior Commissure Involved

Xuekui Liu402 enrolled

Overview

Open surgery and CO2 laser surgery are both established treatment modalities for T1N0 glottic carcinoma. It is controversial for T1N0 glottic carcinoma with anterior commissure involved.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

402

Conditions

Squamous Cell Carcinoma of Glottis

Interventions

CO2 Laser surgeryPROCEDURE

Patients were randomly assigned to CO2 laser surgery group and open Surgery group.

Open SurgeryPROCEDURE

Patients were randomly assigned to CO2 laser surgery group and open Surgery group.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * T1N0 SCC of glottic carcinoma with anterior commissure involve * No nodal metastasis and distant metastasis * All patients must have CT/MR and electronic laryngoscope test before surgery and after surgery * Expected lifetime\>1 year * Patients and families agreed to participate in the test and sign the informed consent * Without cognitive impairment. Exclusion Criteria: * With severe cardiac insufficiency Liver and kidney function is not complete systemic infection patients * Patients with pregnancy and lactation * Have surgery contraindications

Locations (1)

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

RECRUITING

Outcomes

Primary Outcomes

disease-free survival

Time frame: 5 years

Secondary Outcomes

recurrence rate

Time frame: 5 years

Central Contacts

xuekui liu, doctor

CONTACT

(86-20) 8734 3768 liuxk@sysucc.org.cn

Data from ClinicalTrials.gov

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