Bicarbonate in Patients With Out-of-hospital Cardiac Arrest

Asan Medical Center50 enrolled

Overview

A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Cardiac Arrest Metabolic Acidosis

Interventions

Sodium bicarbonateDRUG

Administer Sodium bicarbonate 50 mEq IV over 2 minutes

Normal salineDRUG

Placebo

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adult cardiac arrest patient with arterial pH \<7.1 or bicarbonate \<10mmEq/L checked at 10 minutes of cardiopulmonary resuscitation Exclusion Criteria: * age \<18 trauma patient Do Not Resuscitate state

Outcomes

Primary Outcomes

Return of Spontaneous Circulation (ROSC)

Percentage of Participants with Return of Spontaneous Circulation (ROSC)

Time frame: checked during CPR, duration of ROSC >20 min

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.