Stem Cell Therapy for Patients With Vascular Occlusive Diseases Such as Diabetic Foot

Inclusion Criteria: * the age of 30-78 years old, men and women there is no limit. * in accordance with the ministry of health in higher medical colleges and universities teaching material the sixth edition of the annals of diabetic foot diagnostic criteria. * with severe lower limb ischemia (defined as the resting state of ankle brachial index (ABI) 0.4-0.85, accompanied by resting or intermittent toe line. * treatment on a voluntary basis, and sign the informed consent. Exclusion Criteria: * with severe heart, liver, kidney, lung function failure or general condition is very poor can't tolerate the stem cell transplant. * clear over the past five years tumor markers in patients with malignant disease and blood levels increased significantly. * the prodrome of acute infectious diseases. * participated in clinical subjects within three months before test. * adherence is poor, can not complete the course.