This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.
Taste disorders are frequent side effects in patients undergoing chemotherapy (CTX). Dysguesia has prevalence rates of 16% to 1000% during CTX with sometimes also persistent courses. Impact of dysguesia on appetite, body weight as well as health-related quality of life was shown. Until now, evidence for adequate treatment options is limited to specific diary recommendations. Acupuncture in the treatment of side effects of chemotherapy was investigated for nausea and xerostomia, but not for dysguesia. Therefore, this randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
75
Department of Gynecology & Gynecologic Oncology, Evang. Kliniken Essen-Mitte
Essen, North Rhine-Westphalia, Germany
ACTIVE_NOT_RECRUITINGUniversitätsklinikum Mannheim, Internistische Onkologie
Mannheim, Germany
RECRUITINGRobert Bosch Krankenhaus Stuttgart
Stuttgart, Germany
NOT_YET_RECRUITINGDysgeusia (Phantogeusia) (NRS - Numeric Rating Scale)
Time frame: 7 days
Dysgeusia (Parageusia, Hypogeusia, Hypergeusia) (NRS - Numeric Rating Scale)
Time frame: 7 days
Xerostomia (NRS - Numeric Rating Scale)
Time frame: 7 days
Stomatitis (NRS - Numeric Rating Scale)
Time frame: 7 days
Appetite (NRS - Numeric Rating Scale)
Time frame: 7 days
Impairment (NRS - Numeric Rating Scale)
Time frame: 7 days
Adverse Events (free text)
Time frame: 7 days
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