This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical \& sonographic), which will be used for ICSI in an ART program in Sohag. Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files.
Study approval: The study will be submitted for approval by Research and Ethical committees at Faculty of Medicine, Sohag University. This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical \& sonographic), which will be used for ICSI in an ART program in Sohag . Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files. Study design: Prospective, controlled clinical study. Control group: ICSI cases using cryopreserved sperms from infertile azoospermic men due to etiologies other than varicocele. Cases with known female factor infertility will be excluded. Outcome Measures: fertilization rate, embryo quality, chemical pregnancy and clinical pregnancy.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
16
Intracytoplasmic Sperm Injection
Ajyal Hospital
Sohag, Egypt
RECRUITINGClinical pregnancy: documentation of gestational sac and fetal pulsation by transvaginal US 15 days after B-HCG assessment.
Time frame: 6/2014 up to one year.
Fertilization Rate: percentage of fertilized oocyte.
Time frame: 6/2014 up to one year.
Embryo Quality: morphological assessment of the developing embryo.
Time frame: 6/2014 up to one year.
Chemical pregnancy: B-human chorionic gonadotropin (B-HCG) at day 15 after embryo transfer.
Time frame: 6/2014 up to one year.
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