Ocular Surface Dry Eye Microbiome

University of Washington80 enrolled

Overview

The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dry Eyes

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * dry eye syndrome with OSDI score greater than 60 * control group with OSDI score less than 30 Exclusion Criteria: * recent history of contact lens wear * use of topical antibiotics or prescription eye medication in past 6 months * penetrating ocular surgery in the last 12 months * age less than 18 years

Locations (1)

UW Medicine Eye Institute

Seattle, Washington, United States

RECRUITING

Outcomes

Primary Outcomes

Identification of bacteria or fungus from conjunctival swab

Time frame: 1 month

Central Contacts

Sue Rath, COT

CONTACT

206-897-4331 raths@uw.edu

Data from ClinicalTrials.gov

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