The aim of this observational study is to retrospectively collect current survival data for 3995 primary rectal cancer patients who were extracted from 5097 rectal cancer patients admitted in Cancer Hospital, Chinese Academy of Medical Sciences from January 2000 to December 2010. Moreover, based on a Cox model, we want to develope a nomogram that predicts local recurrence, distant metastases, and survival for patients with rectal cancer treated with pre- or postoperative chemoradiotherapy (CRT).
Study Type
OBSERVATIONAL
Enrollment
3,995
Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)
Beijing, China
Overall survival
Time frame: 5-10 years
Cancer-specific survival
Time frame: 5-10 years
Locoregional recurrence free survival
Time frame: 5-10 years
Distant metastasis free survival
Time frame: 5-10 years
Chemotherapy/Radiotherapy/Chemoradiotherapy toxicities
Chemotherapy toxicities are evaluated by NCI-CTC version 3.0 and radiotherapy toxicities are graded using the RTOG/EORTC Radiation Morbidity Scoring Schema.
Time frame: the duration of hospital stay (an expected average of 6 weeks for chemoradiotherapy and 4-6 months for chemotherapy), as well as within 30 days after completion of the treatment and all the follow-up time
Surgery complication
Time frame: within 30 days after surgery
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