Select Embryos by Time-lapse System for Single Embryo Transfer

Li-jun Ding500 enrolled

Overview

The objective of this study is to establish a hierarchical embryo selection process by using the time-lapse imaging (TLI), combining the embryo cleavage patterns and timing parameters.

The embryos of patients undergoing in vitro fertilization (IVF) treatment is cultured to blastocyst stage and observed by TLI. The association of embryo cleavage patterns/timing parameters and good-quality blastocyst rates are evaluated by logistic regression and to establish a hierarchical embryo selection. The value of the selection process is assess by single embryo transfer (SET) on Day 3.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Embryo

Interventions

time-lapse imagingOTHER

Embryos are observed using time-lapse imaging (Primo Vision®). It is an incubator with a compact, sealed, and digitally inverted camera unit which can automatically acquire images.The system can record the actual developmental stage of the embryos, all the recorded images can be saved to be analyzed later using a special software program.

Eligibility

Sex: FEMALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Women undergoing assistant reproduction treatment Exclusion Criteria: * Oocyte donation cycles

Outcomes

Primary Outcomes

good-quality blastocyst rate

Time frame: 6 days post insemination

Data from ClinicalTrials.gov

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