Topical PDT Cream Without Irradiation Source in the Acne Treatment

Seoul National University Hospital45 enrolled

Overview

In this study, the investigators are going to compare the clinical effect and safety of topical application of 1.5% Butenyl ALA cream formula without light source irradiation in the treatment of acne.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Acne, Photodynamic Therapy

Interventions

Topical application of 1.5% Butenyl ALADRUG

Topical application of sham controlDRUG

Eligibility

Sex: ALLMin age: 19 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * mild to moderate acne vulgaris (Leeds revised acne grading system score 2-7) at baseline. Exclusion Criteria: * known pregnancy * lactation * any medical illness that might influence the results of the study * a history of oral acne medication or surgical procedure, including laser treatment, within 6 months of study enrollment * use of topical acne medication within 4 weeks of study enrollment.

Locations (1)

Seoul National Unviersity

Seoul, Seoul Metropolitan, South Korea

Outcomes

Primary Outcomes

Percent change of inflammatory acne lesions compared with baseline

Time frame: 12 week

Secondary Outcomes

Percent change of non-inflammatory acne lesions compared with baseline

Time frame: 12 week

Percent change of overall severity of acne lesions compared with baseline

Time frame: 12 week

Data from ClinicalTrials.gov

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