Lupus Flares and Histological Renal Activity at the End of the Treatment (LuFla)

Hospital de Clinicas José de San Martín36 enrolled

Overview

At this moment, the duration of the treatment in Proliferative Lupus Nephritis has not been determined. Almost 30 percent of patients in total remission during or after a treatment, will relapse in the first 5 years. The factors associated to Renal relapses are not completly known. The investigators think that an histological control study performed to patient with complete remission for a year at the end of a 3 years treatment could help us to know which patients are going to relapse.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lupus Nephritis

Interventions

Renal BiopsyPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria : * Patients between 18 and 70 years old with Proliferative Lupus Nephritis * 3 years treatment with a 6 month induction therapy and 2 years and a half of treatment maintenence Exclusion Criteria : * Membranous Nephropaty * Mesangial Nephropathy * Less than 3 years treatment * Less than 1 year of complete remission

Locations (1)

Hospital de Clinicas

Buenos Aires, Buenos Aires F.D., Argentina

Outcomes

Primary Outcomes

Renal Flares

Renal relapse after a complete treatment in complete remission patients

Time frame: 2 years

Data from ClinicalTrials.gov

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