Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

Kaohsiung Medical University Chung-Ho Memorial Hospital50 enrolled

Overview

To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Study Type

OBSERVATIONAL

Enrollment

Conditions

Injury to Nerve During Surgery

Interventions

sugammadex (Bridion)DRUG

single dose of sugammadex at skin incision

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * undergoing parotid surgery Exclusion Criteria: * facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease

Locations (1)

I-Cheng Lu

Kaohsiung City, Taiwan

Outcomes

Primary Outcomes

evoked EMG amplitude of facial nerve

Time frame: up to first post-op day

Data from ClinicalTrials.gov

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