The Diagnostic Performance of Tilt Test in Athletes

Aristotle University Of Thessaloniki140 enrolled

Overview

In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt. Moreover, the investigators try to apply a novel algorithm for the improvement of diagnostic yield of tilt test in athletes.

We examine athletes with a history of reflex syncope and athletes without history of reflex syncope.All subjects undergo a tilt test, for the evaluation of haemodynamics, heart rate variability (HRV) and baroreflex sensitivity.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

140

Conditions

Syncope

Interventions

Passive tilt testOTHER

Passive tilt test (without pharmacological provocation). After a horizontal supine rest period of 5 min, the tilt table was inclined at 60° head-up position for 30 min. A positive response was defined according to the European Society of Cardiology guidelines for the diagnosis and management of syncope

Eligibility

Sex: ALLMin age: 14 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 14-40 years old, * more than 5 years of exercise training experience and competition at a regional level at different sports Exclusion Criteria: * smoking, * recent alcohol consumption, * presence of any chronic disease and use of drugs

Locations (1)

Laboratory of Sports Medicine, Sports Medicine Division, Aristotle University of Thessaloniki, Thessaloniki, Greece

Thessaloniki, Greece

Outcomes

Primary Outcomes

sensitivity and specificity of tilt test in athletes as measured by the occurence of syncope/presyncope during tilt test

sensitivity = number of subjects with syncope/presyncope during tilt test/ number of subjects with a history of reflex syncope, specificity = number of subjects without syncope/presyncope during tilt test/ number of subjects without history of reflex syncope

Time frame: 30 min

Secondary Outcomes

Parameters of haemodynamics during tilt test

We investigate whether the mean values of parameters of haemodynamics during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope

Time frame: 30 min

Parameters of heart rate variability during tilt test

We investigate whether the mean values of parameters of heart rate variability during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope

Time frame: 30 min

Parameters of baroreflex sensitivity during tilt test

We investigate whether the mean values of parameters of baroreflex sensitivity during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope

Time frame: 30 min

Data from ClinicalTrials.gov

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