Anthocyanins, the water-soluble compounds that make plants appear different colors, have been shown to prevent insulin resistance, reduce the blood glucose and oxidative stress in rodents. The purpose of our study is to evaluate a potential protective effect of purified anthocyanins supplement on type 2 diabetes mellitus patients.
The study was designed as a randomized, double-blind label, interventional study on patients with T2DM. The eligible Participants are randomly assigned to control and Anthocyanins supplement group. During the 12 weeks trial period,the participants were instructed to consume two anthocyanin capsules or placebo capsules twice daily (30 min after breakfast and supper).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
70
Extract of blueberry and huckleberry (MEDOX,http://www.medox.no/english)
starch
Glycemic Control
Hemoglobin A1c (HbA1c),fasting blood glucose (FBG) at study entry and 12 weeks after dietary intervention
Time frame: Twelve weeks
Biomakers related to oxidative stress
Superoxide dismutase (SOD),Glutathione peroxidase (GSH-PX)
Time frame: Twelve weeks
Blood lipids
Cholesterol, HDL-cholesterol, Triglycerides
Time frame: Twelve weeks
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