Adult Subjects With Uncontrolled Type 2 Diabetes

Inclusion Criteria: 1. Diagnosed with uncontrolled T2DM who have received diet and exercise therapy for at least 3 months prior to screening, aged ≥ 18 - ≤ 75 years 2. Females must be post-menopausal, unable to conceive, or test negative for pregnancy via blood test and use barrier contraception 3. BMI ranging from ≥ 20 to ≤ 40 kg/m2 4. Fasting plasma glucose values of up to 240 mg/dL at screening, after wash-out (visit 2) and after placebo run-in (visit 3) 5. (i) naïve or (ii) currently using and discontinued metformin or (iii) no prior exposure to anti-diabetic agents other than metformin ≥ 6 months prior to screening Exclusion Criteria: 1. History of Type 1 diabetes 2. History of more than 1 episode of severe hypoglycemia within 6 months prior to screening, or a current diagnosis of hypoglycemia unawareness. 3. Hospitalizations or Emergency room visits that would impact patient safety or data interpretation: 1. Due to poor glucose control in the 6 months prior to screening or 2. Any bariatric surgical procedures for weight loss. 4. Significant change of body weight (\>10%) in the 3 months before screening 5. Proliferative retinopathy or maculopathy within the 6 months before screening or requiring acute treatment, or severe neuropathy