The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
Improvements in the surgical treatment of coronary artery disease are possible only when implementation of current methods and development of new methods are based on the solid ground of large and reliable clinical data. Furthermore, clinical findings assume even more significance when detected in study populations from different institutions with heterogeneous referral pathways, baseline clinical characteristics and perioperative treatment strategies. The rationale of this European multicenter study is therefore to prospectively collect data on baseline characteristics, operative and anesthesiological methods and postoperative outcome of patients undergoing CABG in eleven cardiac surgery centers from five European countries. This multicenter prospective registrywill provide data to evaluate the prognostic impact of a number of patients' risk factors as well as the efficacy and safety of operative methods and drugs used during the pre-, peri- and postoperative period.
Study Type
OBSERVATIONAL
Enrollment
4,000
Patients will undergo coronary artery bypass grafting
Oulu University Hospital
Oulu, Finland
RECRUITINGMortality
Any death occurring after surgery
Time frame: The outcome measure will be assessed at time points up to 10 years after surgery
Stroke
Any ischemic brain injury occurring after surgery and lasting \> 24 hours
Time frame: The outcome measure will be assessed at time points up to 10 years after surgery
Prolonged use of inotropes
Use of inotropes \> 12 hours after surgery
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Intra-aortic balloon pump
Use of intra-aortic balloon pump for acute heart failure after surgery
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
ECMO
Use of extracorporeal membrane oxygenation for acute heart failure after surgery
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Repeat revascularization
Any repeat myocardial revascularization procedure performed after surgery
Time frame: The outcome measure will be assessed at time points up to 10 years after surgery
Wound infection
Any deep sternal or lower limb wound infection occurring after surgery
Time frame: Participants will be followed up for 3 months after surgery
Blood losses
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Amont of blood losses from drainages 12 hours after surgery
Time frame: Participants will be followed 12 hours after surgery
Nadir hematocrit
Lowest hematocrit level during the operation day
Time frame: Participants will be followed during the operation day
Use of blood products
Use of any blood product (red blood cell, fresh frozen plasma, Octaplas, platelets) during the in-hospital stay
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Use of prothrombotic drugs
Perioperative use of cryoprecipitate, PCC and/or rFVIIa for excessive bleeding PCCs Perioperative use of rFVIIa, PCC, cryoprecipitate
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Resternotomy for bleeding
Re-exploration for excessive bleeding
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Atrial fibrillation
New episode of atrial fibrillation requiring or not cardioversion during the in-hospital stay
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Renal replacement therapy
Any renal replacement therapy during the in-hospital stay
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Highest level of serum creatinine
Highest level of serum creatinine during the in-hospital stay
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Myocardial infarction
Myocardial infarction (diagnosed by ECG and troponin monitoring) any time after surgery
Time frame: The outcome measure will be assessed at time point up to 10 years after surgery
Length of stay in the intensive care unit
Length of stay in the intensive care unit after surgery
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Pericardial effusion
Pericardial effusion requiring medical or surgical treatment
Time frame: Participants will be followed up to 3 months after surgery.
Postoperative use of antibiotics
Postoperative use of antibiotics for postoperative infection
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)
Gastrointestinal complications
Any gastrointestinal complication requiring medical or surgical treatment after surgery
Time frame: Participants will be followed for the duration of hospital stay (expected: 10 days)