Recording High Frequency Oscillations in Patients With Tumors and Epilepsy

N/AUnknownNCT02320136

University of Zurich120 enrolled

Overview

The investigators want to characterize high-frequency oscillations (HFOs) in intracranial recordings, which may occur as markers of epileptogenic tissue and also under physiological stimulation. The investigators want to show that recording of high-frequency oscillations (HFOs) is feasible in our project population both intraoperatively and during presurgical physiological conditions.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Epilepsy Tumor

Interventions

cognitive testingBEHAVIORAL

patients perform simple tasks like watching a video or memorizing items

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients intend to be treated at the Klinik für Neurochirurgie * Patients fall into one of the patient groups: (1) Patients with symptomatic epilepsy with focal and/or secondary generalized seizures resistant to medication where a neurosurgical resection is considered as an intervention of epilepsy surgery. (2)Patients where a tumor is planned to be resected that has caused preoperative seizures. (3) Patients where a tumor is planned to be resected that has not caused preoperative seizures. * Male and Female subjects 18 years to 99 years of age * Written informed consent after participants' information Exclusion Criteria: * contraindications on ethical grounds * known or suspected non-compliance, drug or alcohol abuse, * enrolment into a clinical trial within last 4 weeks

Outcomes

Primary Outcomes

HFO (high-frequency oscillations) occurrence

Time frame: 1 week

Data from ClinicalTrials.gov

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