This study is investigating the effects of 8 weeks of supplementation with Glucodia™, on glucose parameters, triglycerides and body weight as compared to a placebo. Half of the subjects will be administered Glucodia™, while the other half will receive placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
50
KGK Synergize Inc.
London, Ontario, Canada
Change in glucose response to 2-hour oral glucose tolerance test (OGTT) in subjects taking Glucodia™ versus Placebo
Assessed by the change in the area under the curve in glucose response
Time frame: Baseline and week 8
Change in insulin response to 2-hour oral glucose tolerance test (OGTT) in subjects taking Glucodia™ versus Placebo
Assessed by the change in the area under the curve in insulin response
Time frame: Baseline and week 8
Change in fasting glucose in subjects taking Glucodia™ versus Placebo
Time frame: Baseline, week 4 and week 8
Change in fasting insulin in subjects taking Glucodia™ versus Placebo
Time frame: Baseline, week 4 and week 8
Change in HOMA-IR in subjects taking Glucodia™ versus Placebo
Time frame: Baseline, week 4 and week 8
Change in adiponectin levels in subjects taking Glucodia™ versus Placebo
Time frame: Baseline, week 4 and week 8
Change in lipid panel levels in subjects taking Glucodia™ versus Placebo
Lipid panel includes total cholesterol, triglycerides, HDL, LDL, free fatty acids and non-esterified fatty acids
Time frame: Baseline, week 4 and week 8
Change in body composition in subjects taking Glucodia™ versus Placebo
Assessed via DXA scan
Time frame: Baseline, week 4 and week 8
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Change in body composition in subjects taking Glucodia™ versus Placebo
Assessed via circumference measurements of the arm, thigh, hip and waist and the hip to waist ratio
Time frame: Baseline, week 4 and week 8
Change in body weight in subjects taking Glucodia™ versus Placebo
Time frame: Baseline, week 4 and week 8
Change in appetite in subjects taking Glucodia™ versus Placebo
Assessed using a Satiety VAS scale questionnaire
Time frame: Baseline, week 4 and week 8