Predictive Risk Factors for Pancreatic Fistula Grade C After Pancreaticoduodenectomy

Wakayama Medical University3,000 enrolled

Overview

Pancreatic fistula (PF) grade C, defined by the International Study Group of Pancreatic Fistula (ISGPF) is associated with a life-threatening complication after pancreaticoduodenectomy(PD). The rate of grade C PF has been reported 2.5-6%, however, it is critical complication after PD. A large number of enrolled patients will be needed to clarify the risk factors for grade C PF. Therefore, this study design is prospective large observational study at multi-center in Japan and Taiwan.

Study Type

OBSERVATIONAL

Enrollment

3,000

Conditions

Disease of Pancreatic Head or Periampullary Lesions to Require Pancreaticoduodenectomy

Interventions

pancreaticoduodenectomyPROCEDURE

Eligibility

Sex: ALLMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Disease of pancreatic head or periampullary lesions to require pancreaticoduodenectomy 2. Age: 20 years or older 3. PS (ECOG performance status scale) 0-1 at the time of enrollment 4. Ability to understand and the willingness to sign a written informed consent document Exclusion Criteria: 1. patients with severe respiratory disorder required oxygen inhalation 2. patients with severe liver dysfunction 3. patients with chronic renal failure with dialysis 4. patients who are unfit for this study as determined by the attending physician

Locations (1)

Chang Gun Memorial Hospital

Linkou District, Taiwan

RECRUITING