The present study aims at investigating the effect of ingesting 2 cereal products differing by their SDS content on the kinetics of glucose in healthy volunteers.
The present study will compare the effect of consuming cereal products alone on : * the rates of appearance and disappearance of exogenous and total glucose * the glycemic and insulinemic responses * the postprandial GIP concentrations
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
41
acute evaluation of the effect of ingestion of cereal products differing by their Slowly Digestible Starch content
Institut de Recherches Cliniques de Montréal
Montreal, Quebec, Canada
Rate of appearance of exogenous glucose (RaE)
Postprandial kinetic of RaE
Time frame: T0 to 300 minutes
iAUC RaE
iAUC of RaE over selected intervals over the 300-minute postprandial period
Time frame: T0 to 300 minutes
kinetics of Rate of disappearance of exogenous glucose (RdE), Rate of appearance of total glucose (RaT), Rate of disappearance of total glucose (RdT) and Endogenous glucose production (EGP)
Postprandial kinetics of RdE, RaT, RdT and EGP
Time frame: T0 to 300 minutes
iAUC of RdE, RaT, RdT and EGP
iAUC of RdE, RaT and RdT and dAUC of EGP over selected intervals over the 300-minute postprandial period
Time frame: T0 to 300 minutes
kinetics of glycemia and insulinemia
Pre- and postprandial kinetics of glycemia and insulinemia
Time frame: T-120 to 300 minutes
iAUC of glycemia and insulinemia
iAUC of glycemia and insulinemia over selected intervals over the 300-minute postprandial period
Time frame: T0 to 300 minutes
Kinetics of plasma glucose-dependent insulinotropic peptide (GIP) concentration
Postprandial kinetic of GIP
Time frame: T0 to 300 minutes
iAUC of GIP
iAUC of GIP over selected intervals over the 300-minute postprandial period
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Time frame: T0 to 300 minutes
Kinetics of plasma FFA concentration
Postprandial kinetic of FFA
Time frame: T0 to 300 minutes
dAUC of FFA
dAUC of FFA over selected intervals over the 300-minute postprandial period
Time frame: T0 to 300 minutes