Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?
The investigators plan to investigate the effects of desflurane on oxygenation (prevention of HPV) of OLV compare with propofol which is used in general anesthesia for lung resection. Transesophageal echocardiography (TEE) wiill be used to measure pulmonary blood flow during surgery visible and successively. To confirm the effect of HPV by measuring the change in pulmonary blood flow. The correlation between the blood oxygen concentration and attenuation of blood flow will be investigated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
80
Desflurane group: this group of patients receives desflurane as the main anesthetic agent during one-lung anesthesia. Propofol group: this group of patients receives propofol as the main anesthetic agnet during on-lung anesthesia.
Propofol group:this group of patients receives propofol as the main anesthetic agent during one-lung anesthesia.
University of Juntendo
Bunkyō City, Tokyko, Japan
Oxygenation
Arterial blood gases are monitored.Pulmonary blood flow is measured using transesophageal echocardiogram.
Time frame: prior to surgery to one-hour after extubation
Rapidity of Emergence From Anesthesia
Time to extubation and orientation, where the patient is.
Time frame: one minute after cessation of anethetic agents to one hour after extubation
Quality of Consiousness
quality of consciousness will be assessed using Aldrete score
Time frame: after extubation
Postoperative Nausea and Vomiting
degree of nausea and frequency of vomiting
Time frame: on the postoperative day 1
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