Pilot Study: Intraoperative Clonidine and Postoperative Behaviour

Richard Beringer45 enrolled

Overview

Children who are upset during induction of general anaesthesia are frequently distressed postoperatively and are more likely to demonstrate negative behaviour changes. This pilot study is a randomised controlled study of clonidine vs placebo during anaesthesia to identify whether postoperative behavioural disturbance may be minimised.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Negative Behaviour Change

Interventions

ClonidineDRUG

Comparison between placebo and 2 different concentrations of clonidine

PlaceboDRUG

Eligibility

Sex: ALLMin age: 2 YearsMax age: 10 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age 2 to 10 years inclusive * healthy (ASA 1 or 2) Exclusion Criteria: * inability of parents to understand english

Locations (1)

Bristol Dental Hospital

Bristol, United Kingdom

Outcomes

Primary Outcomes

Number of negative changes on the post-hospitalization behavior questionnaire

Time frame: 24 hours and 7 days

Data from ClinicalTrials.gov

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