The autonomic nervous system state (ANSS) and the autonomic nervous system state index (ANSSi) - two indices derived from the pulse photo-plethysmography analysis - have been recently advocated as a measure of sympathetic activity in the anesthetized patients, but their validity has not been yet demonstrated. We will conduct a study aiming to assess if ANSS and ANSSi reflect autonomic nervous system modulation on cardiovascular system in healthy humans under general anaesthesia.
Study Type
OBSERVATIONAL
Enrollment
52
electrocardiographic and pulse-photoplethysmographic waves of patients under general anesthesia for laparoscopic cholecystectomy will be recorded on a laptop pc for offline analysis of autonomic nervous system modulation a three main time point: 1) at baseline, before general anesthesia induction, 2) five min after tracheal tube placement, 3) five min after pneumoperitoneum insufflation.
Luigi Sacco Hospital
Milan, Italy
autonomic nervous system activity during laparoscopic cholecystectomy (measured by pulse-photoplethysmography and heart rate variability analysis)
assessment of autonomic nervous system activity measured by pulse-photoplethysmography and heart rate variability analysis
Time frame: 120 min
agreement of photoplethysmography and heart rate variability
assessment of agreement between pulse-photoplethysmography and heart rate variability as a measure of autonomic nervous system activity
Time frame: 120 min
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