The primary objective of this study is to compare the evolution of pain profiles among patients suffering from lateral epicondyalgia (tennis elbow) following three types of treatment: PRP-L injection versus type A botulinum toxin injection versus corticoid injection.
The secondary objectives are to compare the following among the three groups: A- The global efficacy of each treatment defined by a minimum reduction of 25% in average pain over the last 24 hours between 0 and 6 months. B- The evolution of average pain over the last 24 hours between 0 and each different time frame (3 weeks, 6 weeks, 3 months and 6 months). C- The evolution of maximum pain scores using nocturnal post-effort (Jamar grip test) visual analog scales (VAS) between day 0, 3 weeks, 6 weeks, 3 months and 6 months. D- The perception of change on the Patient's Global Impression of Change score (PGIC) at 3 and 6 months E- The evolution of PRTEE scores at 0, 3 and 6 months F- Adverse events at 3 weeks, 6 weeks, 3 months and 6 months. G - Quality of life and utility via the SF-12 at 3 and 6 months. H- The consumption of analgesics.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
13
Patients will be treated with an injection of leukocyte and platelet rich plasma.
Patients will be treated with an injection of Type A Botulinum toxin.
Patients will be treated with an injection of Corticoids.
CHRU de Montpellier - Hôpital Lapeyronie
Montpellier, France
CHRU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, France
Visual analog scale (VAS) for pain over the last 24 hours
score varying from 0 to 10
Time frame: 6 months versus Baseline (day 0)
Visual analog scale for pain over the last 24 hours
score varying from 0 to 10
Time frame: Baseline (day 0)
Visual analog scale for pain over the last 24 hours
score varying from 0 to 10
Time frame: 3 weeks
Visual analog scale for pain over the last 24 hours
score varying from 0 to 10
Time frame: 6 weeks
Visual analog scale for pain over the last 24 hours
score varying from 0 to 10
Time frame: 3 months
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