In this study,the investigators want to determine the corelation between circulating nuclearsome and the development of SIRS occured after congenital cardiac surgery, including the serverity of organ damage and inflamation.
Blood was collected from study participants at 6 time points; 1) post-anesthesia induction, 2) post-op hour 0, 3) post-op hour 4, 4) post-op hour 24, 5) post-op hour 48, and 6) post-op hour 72. At each of the 6 time points blood was analyzed for levels of the following:histone,blood routine test , c-reaction protein, procalcitonin, N-terminal pro-brain natriuretic,the hepatorenal function,cardiac function and pulmonary function
Study Type
OBSERVATIONAL
Enrollment
100
Shanghai Children's Medical Center
Shanghai, Shanghai Municipality, China
the perioperation change of histone level
Time frame: preoperation to 72 hours after congential cardiac surgery
the perioperation change of c-reaction protein level
Time frame: preoperation to 72 hours after congential cardiac surgery
the perioperation change of cardiac function
Time frame: preoperation to 72 hours after congential cardiac surgery
the perioperation change of blood routine test
Time frame: preoperation to 72 hours after congential cardiac surgery
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