Fecal Microbiota Transplant for Recurrent Clostridium Difficile Infection

Inclusion Criteria for Recipient: * Between the age of 18 and 100 * Have positive Clostridium difficile polymerase chain reaction (PCR) or toxin * Have symptoms of \> 3 watery loose stools a day for at least 2 consecutive days * Have failed at least one prior standard course of antibiotic therapy. Examples of standard therapy are: * Metronidazole 500 mg three times a day for 10 to 14 days * Vancomycin 125 mg four times a day for 10 to 14 days * Not be pregnant and have negative urine and/or serum human chorionic gonadotropin (hCG) test * Not be taking oral or intravenous steroids in the past three months. * Not on biologic agents, anti-tumor necrosis factor (anti-TNF) agents, cyclosporine, mercaptopurine, azathioprine, methotrexate or chemotherapy in the preceding 3 months * Not have profound immunosuppression: Chemotherapy the preceding 3 months, HIV/AIDS, decompensated cirrhosis * Not be in the Intensive Care Unit * Not be a transplant recipient Exclusion Criteria for Recipient: * Not between the age of 18 and 100 * Does not have positive Clostridium difficile PCR or toxin * Does not have symptoms of \> 3 watery loose stools a day for at least 2 consecutive days * Has not failed at least one prior standard course of antibiotic therapy. Examples of standard therapy are: * Metronidazole 500 mg three times a day for 10 to 14 days * Vancomycin 125 mg four times a day for 10 to 14 days * Is pregnant * Has taken oral or IV steroids in the past three months. * Has taken biologic agents, anti-TNF agents, cyclosporine, mercaptopurine, azathioprine, methotrexate or chemotherapy in the preceding 3 months * Has profound immunosuppression: Chemotherapy the preceding 3 months, HIV/AIDS, decompensated cirrhosis * In the Intensive Care Unit * Is a transplant recipient