Blood Pressure Lowering Effect of Supplementation With Korea Red Ginseng Associated With Reductions in Circulating Lp-PLA2 Activity and Lysophospatidylcholines and an Increase in Dihydrobiopterin in Prehypertensive Subjects

Inclusion Criteria: * nondiabetic, nonobese and prehypertensive subjects with blood pressures ranging 120 - 139 mmHg (systolic) or 80-89 mmHg (diastolic) were enrolled in this study. Exclusion Criteria: * exclusion criteria included previous diagnosed clinical hypertension * self-reported use of antihypertensive medication * abnormal liver or renal function * history of cardiovascular disease * kidney disease * cancer * thyroid or pituitary disease or any other serious life-threatening illness that required regular medical treatment * we also excluded women who were pregnant, breast feeding or intending to become pregnant during the time of study.