Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial

Isfahan University of Medical Sciences90 enrolled

Overview

Total Knee Arthroplasty (TKA) is a common orthopedic surgery usually leads to Bleeding. The null hypothesis of this study was that TA has no effect on post surgical bleeding in patients undergoes TKA.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Knee Arthroplasty, Total

Interventions

Tranexamic AcidDRUG

Normal salineDRUG

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Individuals with osteoarthritis who indicated for primary TKA. Exclusion Criteria: * Previous history of ceberovascular diseases * Previous history of myocardial infarction * Candidates for bilateral TKA

Locations (1)

Amin Nemati

Isfahan, Isfahan, Iran

Outcomes

Primary Outcomes

Hb Level 48 Hours After Total Knee Arthroplasty

Time frame: 48 hours after TKA

Data from ClinicalTrials.gov

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